A Few Examples Bisphosphonates are a group of drugs used to prevent and treat osteoporosis. In addition to taking bisphosphonates, patients are advised to maintain adequate intake of calcium and vitamin D. Deficiencies in calcium can cause muscle cramps, heart palpitations, high blood pressure, insomnia and nervous disorders. The recommened daily allowance (RDA) for calcium ranges from 1000 to 2000 mg per day (usually divided into two daily doses) depending on age and gender. Intake of supplemental calcium should be delayed for at least 60 minutes following oral administration of bisphosphonates to maximize absorption of medication. The major dietary sources of calcium are milk and dairy products, as well as dark green leafy vegetables, broccoli, nuts and whole grains.

Talk to your doctor or pharmacist about taking calcium and vitamin D, especially if you are taking a bisphosphonate.